Alzheimer’s Disease And Oral Bacteria – New Findings


Posted on Jan 07, 2015 by William J. Claiborne, DDS MS

If you think that the bacterial build-up in your mouth from poor oral hygiene is just related to bad breath and cavities, be prepared for a jolt. According to researchers, the bacteria found in gum disease has been linked to brain tissue degeneration. Research has already found links between oral bacteria and heart disease, stroke, diabetes, arthritis, impotency, preterm babies and more. The correlation between oral bacteria and Alzheimer’s disease and dementia adds to a long, devastating list.

In one study, brain tissue samples from patients with and without dementia showed that a particular component of oral bacteria was found in 4 out of 10 Alzheimer’s disease tissue samples. This same bacteria component was not found in any of the brain tissue samples of people who did not have Alzheimer’s disease. This clearly showed an association between oral bacteria and Alzheimer’s disease, and not just a causal association.

Oral bacteria build-up can destroy healthy gum tissues, weakening them. The bacteria is able to enter the bloodstream through tears in diseased gum tissues, which can travel through the bloodstream to the brain. This can lead to degeneration in brain tissue that appears similar to Alzheimer’s disease.

This extensive research was conducted after a previous study on mice infected with specific periodontal bacteria. Researchers in this study found the bacteria traveled to the brain in mice, which prompted further studies involving humans.

An early-stage level of periodontal disease, gingivitis, exists in nearly 97% of the population. Gingivitis is one of the most common diseases found in humans and is more common than the common cold. According to the Centers for Disease Control & Prevention, nearly 64% of adults ages 65 and over have moderate or severe levels of periodontal disease.

The Alzheimer’s Association states that Alzheimer’s disease is the nation’s sixth leading cause of death. It affects over 5 million Americans, with one in three older adults dying from Alzheimer’s or another form of dementia. The World Health Organization cites that about 36 million people globally are affected by Alzheimer’s disease. This figure is predicted to increase to 115 million by the year 2050.

Researchers think these bacterial components found in the brain may trigger a response by the immune system along with pathological changes. It is this chain reaction that the study shows can lead to Alzheimer’s. While the findings do not prove that oral bacteria causes Alzheimer’s disease, the links shown through research thus far are sound reasons to maintain good oral health.

Periodontal disease begins silently. You may not notice it in its early stages. However, gum disease is well underway by the time you see blood when brushing your teeth, have frequent bad breath, experience sore and swollen gums, and have gums that turn red rather than a healthy pink color.

Preventing gum disease requires minimal time and investment. Twice daily brushing (at least two minutes each time) and flossing will help keep oral bacteria to a minimum between your six-month oral hygiene exams and cleanings. If you are a smoker or take medications that are drying to oral tissues, consider hygiene visits every four months.

Alzheimer’s disease is a terrible way to spend those last years of life, and just as bad when we watch (or care for) people we love as they suffer through this nightmare. Keep your mouth as bacteria free as possible and stay involved with your general dentist to lessen your risk.

Gum disease will only worsen without treatment. In addition to creating susceptibility for serious diseases, it is the nation’s leading cause of adult tooth loss. If you are having symptoms of gum disease (as mentioned above), call our office at (828) 274-9440 for an examination.

Smoking & Oral Health


Posted on Dec 22, 2014 by William J. Claiborne, DDS MS

Smokers already know they are taking health risks. However, many smokers are unaware of the negative oral health issues when it comes to tobacco use.

For example, research shows that smokers lose more teeth than nonsmokers. According to the Centers for Disease Control & Prevention, about 20 percent of people over age 65 who have never smoked are toothless, while over 41 percent of daily smokers over age 65 are toothless.

It’s no surprise to Periodontists that following periodontal treatment or any type of oral surgery (including implant placement), patients who smoke have longer healing times with less predictable treatment outcomes. Other oral problems include a heightened risk for oral cancer, bad breath, stained teeth, loss of taste, gum recession, mouth sores, tooth loss and deep wrinkling around the mouth.

As a smoker, you also have a far greater increase for periodontal disease. One reason is your increased susceptibility to calculus. This is the plaque that hardens on teeth and can only be removed through a professional cleaning.

When calculus is not removed, the bacteria it harbors can destroy gum tissue and cause gums to pull away from teeth. As a result, teeth look longer and are more vulnerable to bacteria. As bacteria growth develops into periodontal disease, sore pockets form between teeth and fill with bacteria, destroying tissues and supporting bone. Eventually, the teeth become loose and require removal.

Cigarette smoke contains a deadly mix of more than 7,000 chemicals. Smoking harms nearly every organ of the body and diminishes your overall health. Nearly 50 percent of those who don’t quit smoking will die of smoking-related problems.

Quitting is not easy but the benefits are almost immediate. Your circulation improves, your blood pressure starts to return to normal and breathing becomes easier. You’ll also have a healthier mouth.

A new year is an ideal time to kick the habit. The American Cancer Society’s web site, www.cancer.org, is an excellent resource for smokers who are trying to quit. Or, call us at (828) 274-9440 for more information.

Mouthwash Not A Substitute For Oral Hygiene Routine


Posted on Nov 03, 2014 by William J. Claiborne, DDS MS

Several years ago, I heard Jessica Simpson had announced on an Ellen episode that she brushes her teeth “maybe three times a week.” Simpson said she uses Listerine and flosses everyday and uses “a shirt or something” to wipe her teeth. Claiming her breath is fresh, she feels her mouth has been adequately cleaned.

Being in the field of Periodontics, a dental specialty that focuses on the soft tissues in the mouth and dental implant placement, this misinformed attitude is jolting. By failing to adhere to proven preventive measures of twice-daily brushing, daily flossing and 6-month checkups and cleanings, there is an increased risk for a long list of oral health problems to come.

Plaque, the sticky film of bacteria that clings to teeth and gums, must be removed every 24 hours. In as little as 2 to 3 days, the bacteria begin to attack supporting bone and gum tissues around teeth. This is the beginning of decay and Gingivitis, the initial stage of periodontal disease.

Oral rinses are often best as a temporary breath freshener and an ‘add-on’ to a thorough oral hygiene regimen at home. While some oral rinses do help in the prevention of plaque or slowing the progress of tooth decay, they are ‘aids to’ rather than ‘substitutes for’ proper oral hygiene.

As plaque accumulates, calculus (or tartar), forms on teeth. Calculus is a hard substance formed by bacterial buildup that can only be removed by a dental professional using special tools. As calculus adds to the attack on tooth surfaces and gum tissue, this can lead to advanced gum disease, known as periodontitis. Periodontitis is the nation’s leading cause of adult tooth loss.

For oral rinses designed to temporarily reduce bad breath, most fail to combat the causes of bad breath. They don’t destroy the oral bacteria that cause bad breath nor inactivate odor causing compounds. Many assumed to clean the mouth are ineffective at reducing plaque or halting calculus.

If you frequently use mouthwash because of bad breath, there is an underlying problem that should be addressed by your dentist or a periodontal specialist. Persistent bad breath is a symptom of gum disease, which will only worsen without treatment.

Additionally, when oral bacteria enters the bloodstream through diseased gum tissue tears, it can trigger inflammation elsewhere in the body. The bacteria of periodontal disease has been linked to heart disease, stroke, diabetes, arthritis, memory loss, preterm babies and even impotency. This bacteria can even be transferred from one person to another through kissing or sharing food and beverages.

Some rinses actually do help in the fight against the oral bacteria that forms plaque. For individuals who find it physically difficult to brush and floss, certain oral rinses add some protection against cavities and periodontal (gum) disease. These preferably contain fluoride to protect tooth enamel as well. Too, for our patients who have had periodontal surgery, we typically prescribe an oral rinse to help deter bacteria buildup during the healing process.

If you’d like to add an oral rinse to your oral hygiene routine at home, ask your dentist to recommend a rinse with fluoride or antimicrobial agents to get the best benefit. However, twice daily brushing and flossing, combined with 6-month dental check-ups, is a necessary part of a healthy mouth – and there is no substitute.

Call (828) 274-9440 if you have questions or feel your periodontal health is at risk.

Bleeding Gums NOT A Good Sign!


Posted on Oct 13, 2014 by William J. Claiborne, DDS MS

Unfortunately, many Americans perceive that seeing blood while brushing is a good sign, assuming it shows they’re doing a great job. The fact is – Healthy gums do not bleed while brushing! Bleeding gums indicate a problem that needs to be addressed while treatment can be minimal. Delay only allows the problem to worsen, resulting in more time and expense in the future.

Periodontal (gum) disease is the most common cause (and an early warning sign) for gums that bleed while brushing, it is also the leading cause of adult tooth loss in the U.S. Gum disease begins with gingivitis, which occurs from a bacterial build-up of plaque. This irritates the gums, causing them to bleed and become swollen and tender.

Other contributors can make gum tissue more vulnerable to oral bacteria and the development of gum disease. These include:

   • Overzealous brushing, brushing with a hard bristle toothbrush or using an abrasive substance, such as baking soda. These cause more harm than good to teeth and gum tissue.
   • Drugs can contribute to gums that bleed easily. These include antidepressants, nasal sprays and oral contraceptives.
   • Smoking has a drying effect on gum tissue. Smokers typically have more calculus than non-smokers from the irritation of the chemicals in cigarette smoke.
   • Vitamin K deficiency interferes with the body’s process of blood clotting. This can also result in gums that bleed.
   • Certain changes in hormonal levels can cause red, tender and swollen gums.

When bleeding gums are dealt with in early stages, a thorough dental cleaning and committed oral care regimen at home can often halt the progression of gingivitis leading to gum disease. Act now by seeing a Periodontist for treatment. A Periodontist specializes in the treatment of all phases of gum disease. He or she can work with your dentist to determine an appropriate treatment to restore your smile to a healthy state.

Call (828) 274-9440 to learn more.

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