Tissue Regeneration In Dentistry Is Here & Now!
Posted on Jan 31, 2020 by William J. Claiborne, DDS MS
It may sound far-fetched to think of repairing the urethra by regenerating tissues from the mouth. Yet, it’s being done – with the help of advanced technology.
Stricture of the urethra (the duct that carries urine out of the bladder) affects about 1 percent of the male population. For the one percent who suffer with it, urethral stricture contributes to a severely diminished quality of life.
The condition causes patients to be chronically ill, have low urine flow, pain, urinary infections, urinary stones and can lead to failure of the urinary system. Untreated, life-threatening urinary retention can occur.
Recently, a breakthrough in the surgical treatment of male urethral stricture was reported when over 81 percent of patients with urethral strictures were successfully treated with MukoCell.
MukoCell is a method for tissue-engineered oral mucosa transplantation. It takes a small area of oral mucosa (the secreting tissues in the mouth) that is easily accessible in any patient. (https://www.healtheuropa.eu/treatment-of-mens-disease-with-regenerative-medicine/96925/)
In the past, the most successful treatment for urethral reconstruction was through an oral mucosa graft. However this process requires harvesting a large area of oral tissues. The repercussions can leave patients with persistent pain, bleeding, swelling, sensory loss and oral numbness.
Removing large segments of tissues in the mouth can also cause impaired ability to drink, eat and speak. It can lead to periodontal (gum) disease,tooth loss and dental implant failure along with an increased risk of oral cancer.
MukoCell is a method for a tissue-engineered oral mucosa transplant with even better success rates that the standard grafting procedure. Like our LANAP technology, MukoCell can regenerate tissues, although MukoCell regeneration is through a tissue factory that uses a small piece of the patient’s oral mucosa.
In our Asheville Periodontal dental office, tissue regeneration can be successfully performed in the patient’s mouth. Through our LANAP technology (Laser-Assisted New Attachment Procedure) this highly-advanced method efficiently and effectively treats periodontitis (advanced gum disease).
When it comes to oral structure loss, our LANAP technology is able to stimulate bone regrowth in damaged areas. It can regrow periodontal ligament, alveolar bone (the bony ridge that supports the upper teeth), and regrow the bony film that adheres teeth to the jaw.
LANAP includes a minimally invasive (essentially ‘non-surgical’) PerioLase laser that treats patients with moderate to severe periodontal disease – in as little as one session. It is safe for people with conditions such as diabetes, heart disease, and hemophilia.
LANAP’s laser also eliminates the need for cutting into gum tissues with a scalpel. There are no stitches and patients have minimal discomfort following the procedure.
The advanced technology of LANAP offers a simple yet successful way to rid the infectious bacteria of advanced gum disease. By combating this inflammatory disease, the body is at less risk for systemic inflammation that has been shown to contribute to serious and even deadly health problems.
Overcoming gum disease can help patients to save natural teeth. This means the trauma of tooth loss and decisions for replacement can be avoided.
While we applaud astounding developments in tissue regeneration, MukoCell’s progress reinforces the importance of having a healthy ‘oral cavity’. This is why we committed to include the LANAP protocol into our periodontal dental office, making this cutting edge technology accessible to people all across Western North Carolina.
Although people often think of their smile as ‘teeth,’ the tissues in the mouth are a vital part of your smile, your oral health, and your overall health. They are your blanket of protection that shields vulnerable structures beneath from bacterial destruction. When this covering of gum tissues becomes damaged, LANAP offers an efficient and effective method to restore the healthy state of what was lost.
If you suffer with symptoms of gum disease (tender gums that bleed when brushing, persistent bad breath, or gums that have turned red in color), call our office promptly at 828-274-9440. The condition will only worsen without treatment and could result in tooth loss as well as the release of potent bacteria into the bloodstream.
A Spot In The Mouth May Resolve On Its Own, Or Not. Know When To React.
Posted on Jul 01, 2019 by William J. Claiborne, DDS MS
Having a sore spot in the mouth occurs from time to time. Biting the inside of the cheek, foods that are highly acidic, or stress can all lead to sores.
Some viruses and other conditions can contribute to worse problems, however. It is important to know what to look for when it comes to an unusual spot in the mouth. Knowing when to watch and when to see a dentist could be a literal lifesaver.
Fortunately, most sores in the mouth resolve on their own. These include…
Small ulcers with a white or gray base and a red border. Unlike cold sores, canker sores appear inside the mouth. They are not contagious but their exact cause is uncertain. Some experts believe that immune system problems, bacteria or viruses may be involved. Fatigue, stress or allergies can increase the likelihood of a canker sore. A cut caused by biting the cheek or tongue, or reactions from hot foods or beverages may contribute to canker sore development. Intestinal problems, such as ulcerative colitis and Crohn’s disease, also seem to make some people more susceptible. Canker sores usually heal on their own after a week or so. Over-the-counter topical anesthetics, steroid preparations, and antimicrobial mouth rinses can provide temporary relief.
Also called fever blisters or Herpes simplex, these are groups of fluid-filled blisters that often erupt around the lips, under the nose, or around the chin. Cold sores caused by herpes virus type 1 are very contagious. Herpes lesions look like multiple tiny fluid-filled blisters that are most common around the edge of the lips. An outbreak may follow a fever, sunburn, skin abrasions or emotional upset. Cold sore blisters usually heal in a week by themselves. Over-the-counter topical anesthetics can provide some relief. Prescription antiviral drugs may reduce the duration of these kinds of viral infections.
Leukoplakia cause one or more white patches or spots (lesions) to form inside the mouth. Most who have the condition are males between the age 50 – 70. Although leukoplakia can be caused by a rough tooth or an irregular surface on a denture or a filling, it is often associated with heavy smoking or other tobacco and heavy alcohol. In some cases, however, the cause cannot be determined. Leukoplakia is especially concerning because it can eventually develop into oral cancer.
What will NOT resolve on its own and requires prompt evaluation are changes to oral tissue that do not heal within 14 days. DO NOT DELAY! This is a symptom of Oral Cancer. Nearly 40,000 Americans are diagnosed with oral or oropharyngeal (throat) cancer each year. These cancers kill about 1 person every hour, every day.
Symptoms of Oral Cancer that are most common include:
• white or red patch of tissue
• lesion in the mouth
• difficulty or discomfort when swallowing
• persistent sore throat
• a lump or mass inside the mouth or neck
• wart-like mass
• numbness in the oral/facial region
The survival rate is one of the worst of all cancers, with only 57 percent estimated to be living 5 years from diagnosis. The death rate is higher than cervical cancer, Hodgkin’s lymphoma, laryngeal cancer, cancer of the testes, thyroid cancer, or skin cancer (malignant melanoma).
Although the death rate has seen a slight decrease since 1980, some symptoms do not emerge until the cancer has reached advanced stages. This is because lesions or discolorations that are early warning signs are not always visible, particularly in the back portion of the mouth (the oropharynx, the tonsils, and base of tongue), which can be an obstacle to early diagnosis and treatment.
This is yet another reason that keeping your regular oral hygiene exam and cleanings is so important. During these times, your dentist and hygienist look for unusual changes in the mouth that can indicate a problem. Please remember – NEVER wait until your scheduled appointment to have anything unusual examined.
Although a stubborn canker or cold sore may not be welcome, they tend to go away in a week or ten days. Again, if an unusual spot or sore is still present after two weeks, call our Asheville periodontal office at 828-274-9440 immediately for an appointment.
Cancer Risk And Gum Health
Posted on Feb 05, 2019 by William J. Claiborne, DDS MS
I know of no one who hasn’t lost someone dear to them – family member or close friend – to cancer. The disease, although now more survivable than ever thanks to advancements in early detection and treatment – remains a dreaded diagnosis.
Still, a cancer diagnosis often drags entire families through the battle. Treatment can be lengthy and time-consuming as well as financially and emotionally draining. Some diagnoses are considered ‘death sentences,’ with terribly low survival rates. For instance, pancreatic cancer’s 5-year survival rate, depending on the type, ranges between 3 – 9 percent. (https://www.pancan.org/facing-pancreatic-cancer/about-pancreatic-cancer/survival-rate/)
Decades of research has resulted in improved measures, and many cancers once thought dooming are now very treatable. Success rates are improving with most survivors going on to live normal, healthy, active lives.
Preventing cancer isn’t a simple matter. We know that a healthy lifestyle can help but isn’t a guarantee for avoiding it. Cancer can result from a number of triggers. For example, smoking is a known contributor to oral and lung cancer. The toxic chemicals delivered through cigarette smoke are proven activators in some cancer development.
As research has been able to go deeper into the cause-&-effect of various cancers, the health of periodontal tissues are coming to light as having an intricate role in your overall health, including your risk for developing some cancers.
Periodontal disease, often referred to as gum disease, runs rampant in the U.S. According to the Centers for Disease Control & Prevention (CDC), over 47 percent of adults over the age of 30 have some level of gum disease. For adults over the age of 65, this figure increases to 70 percent.
This is a frightening statistic considering the devastation that infectious bacteria of periodontal disease can cause. While it is the nation’s leading cause of adult tooth loss, research has also revealed links to increased risk of heart disease, stroke, arthritis, diabetes, preterm babies, high blood pressure, and erectile dysfunction (ED).
Yet, much progress is being made in tracking down activators of cancer in the body. For instance, research shared in a January 2018 article in Medical News Today revealed exciting progress along these lines. (https://www.medicalnewstoday.com/articles/320634.php)
Researchers found that some gastrointestinal cancers, such as pancreatic cancer, share an enzyme. This enzyme, typically found in the mouth, serves as the “boosting” agent in the development of gum disease. They noted that the enzyme was also present in certain cancerous tumors.
In additional research shared by the AACR (American Association For Cancer Research), cited that previous research has revealed gum disease as a risk factor for breast, oral, and esophageal cancers. (https://www.aacrfoundation.org/Science/Pages/assessing-gum-disease-cancer-risk.aspx). The warn that women, especially, should be urged to maintain good periodontal disease to lower their risk of additional types of cancer.
One study showed that post-menopausal females were more susceptible to several cancers.
Between 1999 – 2003, researchers monitored cancer outcomes of female participants ages 54 to 86 through self-reported questionnaires onn periodontal disease. The study showed that: “a history of gum disease was associated with a 14 percent higher risk of developing any cancer”.
The greatest association was for cancer of the esophagus, which was more than 3 times more likely in women with periodontal disease than women who did not list having periodontal disease. Lung cancer, gallbladder cancer, melanoma, and breast cancer were also associated with higher risk.
Although women who smoked had higher risks for breast cancer, lung cancer, and gallbladder cancer, non-smokers with gum disease also had increased risks of these cancers.
Still not fully understood, it is suspected that gum disease bacteria are able to enter the bloodstream through diseased gum tissues. This allows them to reach other body sites and contribute to “carcinogenesis”, the process where normal cells are transformed into cancer cells, leading to the formation of cancer.
Because the study consisted of self-reported data, the study’s authors suspect the prevalence of periodontal disease may have been under-reported. This would make the percentages even higher. While further research is needed through more precise assessments of periodontal disease, these statistics are helpful in confirming the link between periodontal disease and cancer.
This study also reinforces previous findings that show our oral health is more closely related to our overall health than most are aware. As a periodontal specialist, I urge you to be aware of the signs and symptoms associated with all stages of gum disease. These include tender gums that bleed easily when brushing, gums that turn red in color, frequent bad breath, and gums that loosen their grip around teeth.
For more, you may find it helpful to visit the web site of the American Academy of Periodontology: www.perio.org.
A periodontist is a dental specialist with advanced training in the diagnosis and treatment of all stages of gum disease. This advanced care is your wisest choice for tackling gum disease and having good oral health at any age. For more information or to schedule an appointment, call 828-274-9440 or tap here to begin.
Start The New Year With A Smile That Enhances Your Life!
Posted on Dec 31, 2018 by William J. Claiborne, DDS MS
As we look at the new year, many of us are setting goals for positive changes in our lives. Whether we aim to lose weight, tackle an upcoming 10k run, or kick a bad habit, a new year resets our enthusiasm and motivation to improve.
And oft-overlooked area that many Americans should add to their “need to improve” list is caring for their oral health. According to the Centers for Disease Control & Prevention (CDC), over 47 percent of the adult population in the U.S. has some level of periodontal (gum) disease.
So, this year, I’d like you to relook at the list you’ve already made and consider adding “improve oral wellness” to it.
Although a clean, healthy mouth gives you a better-looking smile and fresher breath, there are even more important reasons to maintain excellent gum health. Not only is periodontal disease the nation’s leading cause of adult tooth loss, it has been linked serious health risks. This includes heart disease, high blood pressure, memory loss, arthritis, diabetes, preterm babies and impotency.
Gum disease can begin silently, with warning signs that are not obvious or may be easily ignored. It may be first noticed by sore spots on gum tissues. You may notice some blood in the sink when brushing teeth. Your mouth may feel sticky and you have bad breath more frequently.
When these signs are ignored, gum disease is allowed to progress further. The symptoms of gum disease are:
- Red, swollen or tender gums or other sore areas in your mouth
- Bleeding while brushing or flossing
- Gums that recede or pull away from teeth, causing the teeth to look longer than before
- Loose or separating teeth
- Pus pockets between your gums and teeth
- Persistent bad breath
- A change in the way your teeth fit together when you bite
- A change in the fit of partial dentures
You can also learn about the stages of gum disease on the web site of the American Academy of Periodontology: (https://www.perio.org/consumer/types-gum-disease.html).
Your mouth also sends off warning signs when something is wrong. For example, an ache coming from a tooth may indicate a cavity or crack. A sore spot in the mouth could be caused by a canker sore or warning sign of oral cancer.
Some periodontal needs can be managed by their general dentist. However, as signs of periodontal disease continue, periodontal treatment may require the skills of a specialist. Patients who have moderate or severe levels of periodontal disease, or patients with more complex cases, are often best managed through ‘team treatment’ between a general dentist and periodontal specialist.
The American Academy of Periodontology defines a periodontist as “a dentist who specializes in the prevention, diagnosis, and treatment of periodontal disease, and in the placement of dental implants. Periodontists are also experts in the treatment of oral inflammation. Periodontists receive extensive training in these areas, including three additional years of education beyond dental school. They are familiar with the latest techniques for diagnosing and treating periodontal disease, and are also trained in performing cosmetic periodontal procedures.
“Periodontists often treat more problematic periodontal cases, such as those with severe gum disease or a complex medical history. Periodontists offer a wide range of treatments, such as scaling and root planing (in which the infected surface of the root is cleaned) or root surface debridement (in which damaged tissue is removed). They can also treat patients with severe gum problems using a range of surgical procedures.
“In addition, periodontists are specially trained in the placement, maintenance, and repair of dental implants.”
However, if you are experiencing signs of periodontal disease and do not have a regular dentist, please know that you do not have to be referred to our office for care. Once your mouth is restored to optimal health, we can suggest a general dentist for you if you do not have one.
Don’t delay seeking care when you notice the first warning sign. Early treatment may save you greatly in time and expense – and even help you avoid tooth loss! Once your mouth is restored to a healthy state, we’ll help you maintain it by recommending home care steps combined with periodic check-ups.
If your obstacle has been fear of dentistry, we have an excellent reputation for helping fearful dental patients overcome these. We also offer oral and I.V. sedation (twilight sleep) that help patients feel more relaxed during treatment.
Or, if you feel you can’t manage the expenses associated with dental care, we offer several payment plans. Through these, you can afford to achieve a healthy smile while making easy, monthly payments.
Begin with a consultation or ask for an initial periodontal exam by calling 828-274-9440. Let our specialized skills in periodontics help to restore your teeth and gums to excellent oral health and confident smiles!